Endocrine Abstracts

Introduction: Primary aldosteronism (PA) is a common cause of secondary hypertension that can lead to renal sequelae. Treatment of hyperaldosteronism leads to reductions in albuminuria and glomerular hyperfiltration. We aimed to evaluate the effect of treatment on albuminuria and temporal changes in renal function after treatment with both surgery and medications.Methods: We prospectively recruited patients with PA over three years. Spot urine samples fo...

Introduction: Elevated low-density lipoprotein cholesterol (LDL-C) is an important risk factor for atherosclerotic cardiovascular disease (ASCVD). Direct LDL-C measurement is not widely performed. LDL-C is typically estimated using the Friedewald (FLDL), Martin-Hopkins (MLDL) or Sampson (SLDL) equations, which may be inaccurate at high triglycerides (TG) or low LDL-C levels. We aimed to determine if machine learning (ML)-derived LDL-C levels agree better with direct LDL-C than...